1. Weakness -Patients become extremely weary during and after exposure to such high levels of radiation. This can also linger for several weeks after treatment.
  2. Reaction on the skin- Radiation causes peeling, itching, and blistering of the skin. The skin may turn dark or red in the treatment areas and on the other side of the body when the treatment is performed. It's possible that these places will get inflamed. This discomfort can linger for two to four weeks after treatment.
  3. Diarrhoea- Gallbladder cancer radiation therapy can cause inflammation in the gut lining, resulting in diarrhoea. Cramps and unusual stools are possible side effects.
  4. Nausea- When radiation is applied to the gallbladder, it affects the surrounding organs, such as the stomach and intestines, causing nausea and vomiting. This creates digestive problems, which can lead to vomiting and weakness.
  5. Problems with eating and drinking-Patients who receive radiotherapy for metastasized gallbladder cancer frequently feel heartburn and indigestion, making it difficult for them to eat their regular diet.
  6. Weight loss-Patients who lose their appetite during or after treatment lose a lot of weight, especially when radiation for gallbladder cancer is combined with other treatments.
  1. Renal failure-When radiation is used to treat metastasized gallbladder cancer, it may also affect the kidneys, resulting in renal failure, which is a condition in which the kidneys' ability to filter water out of the body is impaired. This could potentially have an impact on the urine bladder.
  2. Heart issues- Radiation to any region of the body can cause blood pressure and heart rhythm irregularities, which can lead to long-term heart difficulties.
  3. Abnormalities in blood cell count- A high dose of radiation can cause a drop in the body's blood cell count. Damage to healthy blood cells during therapy can result in a blood cell count anomaly, which can lead to the following:
  • Anemia is a condition in which the body's red blood cells are depleted, resulting in extreme weakness.
  • Infections are more likely in patients with a low white blood cell count.
  • Bleeding: A low platelet count can make blood clotting harder.
  1. Hair loss- Radiation therapy affects hair follicles as well. Because they are extremely sensitive, this treatment can result in significant hair loss.
  2. Damage to the liver- occurs when radiation is supplied to the gallbladder, which can cause problems with the liver's function.

The majority of side effects subside within one to two weeks after treatment. Patients, on the other hand, must live with the long-term negative effects for the rest of their lives. To lessen the influence of the above side effects on the body, patients must adhere to a tight and closely monitored post-treatment follow-up plan.