Stomach cancer can be treated with a variety of chemotherapy medicines, including
- 5-FU (fluorouracil), which is frequently given in combination with leucovorin (folinic acid)
- Irinotecan (Camptosar)
- Capecitabine is a drug that is used to treat cancer (Xeloda)
- Docetaxel is a drug that is used to treat cancer (Taxotere)
- Epirubicin (Ellence)
- Oxaliplatin (Eloxatin)
- Paclitaxel (Taxol)
These medications may be administered alone or in combination with other chemotherapy or targeted drugs, depending on the scenario (such as the stage of the disease, the person's overall health, and whether chemo is paired with radiation therapy).
When surgery is anticipated, some frequent medication combinations include:
- ECF (epirubicin, cisplatin, and 5-FU) is a chemotherapy drug that can be used before and after surgery.
- As a pre-surgery treatment, docetaxel or paclitaxel plus either 5-FU or capecitabine, coupled with radiation
- As a pre-surgery treatment, paclitaxel and carboplatin were coupled with radiation.
- Cisplatin plus either 5-FU or capecitabine, together with radiation, was used as a pre-surgery treatment.
When chemo and radiation are combined after surgery for stomach cancer, a single medication, such as 5-FU or capecitabine, may be utilised.
ECF may be used to treat advanced stomach cancer, but other combinations may be more effective. Here are a few examples:
- Irinotecan plus cisplatin
- Irinotecan plus 5-FU or capecitabine
- DCF (docetaxel, cisplatin, and 5-FU)
- Capecitabine or oxaliplatin with 5-FU
To treat advanced stomach cancer, many doctors opt to combine two chemo medicines. Because three-drug combos can have greater adverse effects, they're normally reserved for those in good health who can be closely monitored by their doctor.